Sorry, I am having trouble understanding your meaning. The obvious answer is that one is 2200 and the other is bigger. 'though I doubt that this is the answer you are looking for.
What I think you may be after, is that there is none, as long as you can physically fit the bigger battery. other than you will have a longer flight time. As long as the voltage is the same. The "Phantom" battery is nominally 11.1 volts. If you exceed this you will find very interesting, VERY expensive smoke coming out of the main body.